Severe Combined Immunodeficiency (SCID) is a group of medical disorders that result from genetic defects in both cellular and humoral immunity. Those immune defects lead to infections with bacterial, viral, and fungal pathogens that begin during infancy and, if untreated, result in a fatal outcome in the first few years of life
Other forms of SCID are caused by a deficiency of the enzyme adenosine deaminase (ADA) and a variety of other genetic defects.
SCID (pronounced "skid") is a "combined" immunodeficiency because it affects both of these infection-fighting white blood cells.